Oporinus’ printer’s mark appeared for the first time in the first edition of the Fabrica. It was allegedly suggested to him by Vesalius. It depicts Arion, a Greek singer and poet who was kidnapped by pirates and rescued by dolphins after he leaped into the sea to escape. The motto invia virtue nulla est via – no path is impassable to virtue – is the words spoken by the Sibyl to Aeneas before his descent into the Underworld.